Steven Brem Selected Research

Glioma (Gliomas)

1/2023	Mismatch repair protein mutations in isocitrate dehydrogenase (IDH)-mutant astrocytoma and IDH-wild-type glioblastoma.
1/2023	Commentary: Complementary and Alternative Medicine for Gliomas: Systematic Review and Critical Appraisal of Current Literature.
12/2020	Effect of Vocimagene Amiretrorepvec in Combination With Flucytosine vs Standard of Care on Survival Following Tumor Resection in Patients With Recurrent High-Grade Glioma: A Randomized Clinical Trial.
10/2020	Near-Infrared Imaging with Second-Window Indocyanine Green in Newly Diagnosed High-Grade Gliomas Predicts Gadolinium Enhancement on Postoperative Magnetic Resonance Imaging.
11/2019	Negative prognostic impact of epidermal growth factor receptor copy number gain in young adults with isocitrate dehydrogenase wild-type glioblastoma.
9/2016	Non-invasive detection of 2-hydroxyglutarate in IDH-mutated gliomas using two-dimensional localized correlation spectroscopy (2D L-COSY) at 7 Tesla.
10/2014	Senescence-associated-gene signature identifies genes linked to age, prognosis, and progression of human gliomas.
8/2010	Impaired orthotopic glioma growth and vascularization in transgenic mouse models of Alzheimer's disease.
8/2006	In vitro drug response and molecular markers associated with drug resistance in malignant gliomas.
9/2005	Local treatment of malignant brain tumors using implantable chemotherapeutic polymers.

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Steven Brem Research Topics

Disease

42	Glioblastoma (Glioblastoma Multiforme) 01/2024 - 07/2005
40	Neoplasms (Cancer) 01/2024 - 09/2002
15	Glioma (Gliomas) 01/2023 - 09/2002
9	Brain Neoplasms (Brain Tumor) 01/2023 - 08/2003
4	Astrocytoma (Pilocytic Astrocytoma) 01/2023 - 08/2003
3	Alzheimer Disease (Alzheimer's Disease) 08/2010 - 01/2004
3	Neoplasm Metastasis (Metastasis) 06/2007 - 05/2004
2	Lymphoma (Lymphomas) 08/2023 - 01/2005
2	Necrosis 01/2019 - 03/2008
2	Hypoxia (Hypoxemia) 01/2018 - 05/2008
2	Amyloid Plaque 03/2008 - 01/2004
2	Melanoma (Melanoma, Malignant) 07/2006 - 05/2004
1	B-Cell Lymphoma (Lymphoma, B Cell) 08/2023
1	Intracranial Hemorrhages (Intracranial Hemorrhage) 12/2022
1	Mitochondrial Diseases (Mitochondrial Disease) 12/2017
1	Oligodendroglioma 01/2017
1	Cytokine Release Syndrome 01/2017
1	Dementia (Dementias) 08/2010
1	Meningioma (Meningiomas) 03/2007
1	Exanthema (Rash) 07/2005
1	Hepatolenticular Degeneration (Wilson's Disease) 07/2005

Drug/Important Bio-Agent (IBA)

6	Temozolomide (Temodar)FDA LinkGeneric 01/2023 - 08/2006
5	Biomarkers (Surrogate Marker)IBA 01/2020 - 08/2006
5	Carmustine (FIVB)FDA Link 11/2013 - 09/2002
4	epidermal growth factor receptor VIIIIBA 01/2024 - 01/2017
4	VaccinesIBA 05/2023 - 01/2018
4	Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA 01/2023 - 09/2016
4	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2018 - 05/2004
3	Indocyanine Green (Cardio-Green)FDA LinkGeneric 08/2023 - 10/2020
3	RNA (Ribonucleic Acid)IBA 10/2021 - 01/2019
3	Interleukin-6 (Interleukin 6)IBA 01/2021 - 10/2014
3	Cell-Free Nucleic AcidsIBA 01/2021 - 01/2020
3	DNA (Deoxyribonucleic Acid)IBA 01/2021 - 01/2020
3	Peptides (Polypeptides)IBA 08/2010 - 01/2004
2	Interleukin-4 Receptors (Interleukin 4 Receptor)IBA 01/2023 - 01/2021
2	Amino Acids FDA Link 01/2023 - 01/2023
2	ErbB Receptors (EGF Receptor)IBA 01/2021 - 11/2019
2	Chimeric Antigen ReceptorsIBA 01/2021 - 01/2019
2	Antimitotic AgentsIBA 12/2017 - 01/2016
2	Irinotecan (Camptosar)FDA LinkGeneric 01/2012 - 08/2006
2	Bevacizumab (Avastin)FDA Link 01/2012 - 04/2011
2	PolymersIBA 06/2007 - 09/2005
1	InterferonsIBA 01/2024
1	Monoclonal AntibodiesIBA 01/2024
1	pembrolizumabIBA 01/2024
1	Proteins (Proteins, Gene)FDA Link 01/2023
1	Contrast MediaIBA 01/2023
1	Gadolinium DTPA (Magnevist)FDA Link 01/2023
1	AnticoagulantsIBA 12/2022
1	Low-Molecular-Weight Heparin (Heparin, Low Molecular Weight)IBA 12/2022
1	ApoferritinsIBA 02/2022
1	AminesIBA 01/2021
1	Combined Antibody TherapeuticsIBA 01/2021
1	Immunotoxins (Immunotoxin)IBA 01/2021
1	vocimagene amiretrorepvecIBA 12/2020
1	Flucytosine (Ancobon)FDA Link 12/2020
1	GadoliniumIBA 10/2020
1	AcidsIBA 01/2020
1	Circulating Tumor DNAIBA 01/2020
1	CateninsIBA 01/2020
1	thiamine triphosphorate (TTP)IBA 11/2019
1	Tyrosine Kinase InhibitorsIBA 11/2019
1	osimertinibIBA 11/2019
1	HemosiderinIBA 01/2019
1	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 01/2018
1	Vascular Endothelial Growth Factor Receptor-2 (Vascular Endothelial Growth Factor Receptor 2)IBA 01/2018
1	NucleotidesIBA 12/2017
1	AntigensIBA 01/2017
1	EnzymesIBA 09/2016
1	alpha-hydroxyglutarateIBA 09/2016
1	Annexin A5IBA 04/2016
1	Serine (L-Serine)FDA Link 04/2016
1	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 10/2014
1	Interleukin-8 (Interleukin 8)IBA 10/2014
1	Insulin-Like Growth Factor Binding Protein 3IBA 10/2014
1	Insulin-Like Growth Factor Binding ProteinsIBA 10/2014
1	Hydroxychloroquine (Plaquenil)FDA LinkGeneric 08/2014
1	Neoplasm Antigens (Tumor Antigens)IBA 07/2013
1	LigandsIBA 07/2013
1	AntibodiesIBA 07/2013
1	Vorinostat FDA Link 01/2012
1	matrigelIBA 08/2010
1	Amyloid beta-PeptidesIBA 08/2010
1	Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA 05/2008
1	Peptide FragmentsIBA 03/2008
1	Cisplatin (Platino)FDA LinkGeneric 08/2006
1	CopperIBA 07/2005
1	Penicillamine (Cuprimine)FDA Link 07/2005

Therapy/Procedure

18	Therapeutics 01/2023 - 07/2005
11	Radiotherapy 01/2023 - 09/2002
6	Drug Therapy (Chemotherapy) 01/2023 - 09/2005
5	Immunotherapy 01/2021 - 01/2005
4	Craniotomy 08/2023 - 06/2007
4	Chemoradiotherapy 01/2023 - 12/2017
2	Aftercare (After-Treatment) 01/2020 - 11/2013
1	Complementary Therapies (Alternative Medicine) 01/2023
1	Length of Stay 10/2020
1	Patient Readmission 10/2020
1	Surgical Navigation Systems 03/2020
1	Computer-Assisted Surgery (Image Guided Surgery) 05/2008